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The Centre for Microbiome Research (CMR) within the School of Biomedical Sciences at QUT is looking for talented individuals to undertake PhDs applying cutting-edge laboratory and bioinformatic approaches to the study of complex microbial communities across a range of topics and environments.
昆士兰科技大学生物医学科学学院的微生物组研究中心 （CMR） 正在寻找有才华的人攻读博士学位，应用尖端的实验室和生物信息学方法研究一系列主题和环境中的复杂微生物群落。
These PhD positions will be supervised by Associate Professor Simon McIlroy, Professor Phil Pope and Professor Gene Tyson.
这些博士职位将由 Simon McIlroy 副教授、Phil Pope 教授和 Gene Tyson 教授监督。
International applicants are welcome.
欢迎国际申请者。
- Gut microbiome impacts in animal health and nutrition
肠道微生物组对动物健康和营养的影响
The gut microbiome has major influence in the health and nutrition of mammals and is a particular focal point in research dedicated to improving human wellbeing and the sustainability and environmental impact of production animals.
肠道微生物组对哺乳动物的健康和营养有重大影响，是致力于改善人类福祉以及生产动物的可持续性和环境影响的研究的特别焦点。
These PhD projects will aim to improve understanding into the intimate relationships between gut microbes and dietary fibre, with gained knowledge applied to the design and application of prebiotic fibres otherwise known as microbiota-directed fibres (MDFs).
这些博士项目将旨在提高对肠道微生物和膳食纤维之间密切关系的理解，并将所获得的知识应用于益生元纤维（也称为微生物群定向纤维 （MDF））的设计和应用。
The project will apply state-of-the-art lab and computational-based molecular tools to study combinations of pure culture, synthetic microbial consortia and in vitro enrichments.
该项目将应用最先进的实验室和基于计算的分子工具来研究纯培养、合成微生物联盟和体外富集的组合。
Expected learning outcomes are enhanced microbiome monitoring and predictive capabilities that will improve the application of MDFs and precision microbiome reprogramming strategies.
预期的学习成果是增强的微生物组监测和预测能力，这将改善 MDF 的应用和精确的微生物组重编程策略。
- Metabolic diversity of the anaerobic methanotrophic (ANME) archaea mediating methane oxidation in freshwater environments
厌氧甲烷营养型 （ANME） 古细菌介导淡水环境中甲烷氧化的代谢多样性
The as-yet uncultured archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of the potent greenhouse gas methane—making them critical to maintaining Earth’s climate.
尚未培养的古细菌谱系 Methanoperedenaceae 是厌氧嗜甲烷菌，在减轻大气中强效温室气体甲烷的释放方面发挥着关键作用，这使得它们对维持地球气候至关重要。The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.
这些微生物的代谢多样性将甲烷与几个关键的生化循环直接联系起来，并表明这些微生物具有适应不同环境条件的非凡能力。The overall aim of this PhD project will be to uncover the metabolic diversity of the Methanoperedenaceae and to understand the evolutionary mechanisms responsible for these adaptations (i.e. mobile genetic elements such as plasmids and viruses).
本博士项目的总体目标是揭示 Methanoperedenaceae 的代谢多样性，并了解负责这些适应的进化机制（即移动遗传元件，如质粒和病毒）。
The project will utilise cutting-edge synthetic biology, meta-omic and single cell visualisation techniques.
该项目将利用尖端的合成生物学、元组学和单细胞可视化技术。
- Understanding microbial responses to climate change
了解微生物对气候变化的反应
Permafrost thaw induced by climate change will make up to 174 Pg of near-surface carbon available for microbial degradation and emission as CO2 and CH4 into the atmosphere.
气候变化引起的永久冻土融化将产生多达 174 Pg 的近地表碳，可用于微生物降解，并以 CO2 和 CH4 的形式排放到大气中。This project will aim to improve prediction of these processes through genome-centric meta-omic analysis of microbial communities in northern Sweden, where a decade of intense molecular and biogeochemical study has been undertaken.
该项目旨在通过对瑞典北部的微生物群落进行以基因组为中心的元组学分析来改进对这些过程的预测，那里已经进行了十年的深入分子和生物地球化学研究。This dataset provides a unique opportunity to examine how microbial communities are changing alongside our climate.
该数据集提供了一个独特的机会来研究微生物群落如何随着我们的气候而变化。
The overall aim of this project is to examine how individual microbial community members and entire communities assemble, adapt and acclimatise to changing environmental conditions.
该项目的总体目标是研究单个微生物群落成员和整个群落如何聚集、适应和适应不断变化的环境条件。
More about the CMR and our projects
有关 CMR 和我们项目的更多信息
The projects will be based at the CMR located at the Translational Research Institute (TRI) in Woolloongabba, Brisbane.
这些项目将位于布里斯班乌龙戈巴的转化研究所 （TRI） 的 CMR。
CMR was established in 2020 by Professor Tyson, an expert in the field of bioinformatics and microbial ecology.
CMR 由生物信息学和微生物生态学领域的专家 Tyson 教授于 2020 年创立。
Professor Tyson and his team are actively involved in the development of innovative culture-independent molecular approaches and bioinformatic tools, and their application to answer important questions about microbial communities across a range of ecosystems. The team is made up of researchers with diverse expertise within microbial ecology and genomics, providing an intellectually robust and collaborative environment.
Tyson 教授和他的团队积极参与创新培养独立分子方法和生物信息学工具的开发，并将其应用于回答有关一系列生态系统中微生物群落的重要问题。该团队由在微生物生态学和基因组学方面具有不同专业知识的研究人员组成，提供了一个智力强大的协作环境。
As part of CMR the successful student will have access to state-of-the-art computing and laboratory facilities.
作为 CMR 的一部分，成功的学生将可以使用最先进的计算和实验室设施。
About the scholarship 关于奖学金
The successful applicant will receive a living allowance stipend, tax exempt and indexed annually of $33,637 per annum for a period of three years with a top-up of $2,000 per annum for outstanding applicants.
成功的申请人将获得每年 33,637 澳元的生活津贴津贴、免税和指数化，为期三年，优秀申请人每年可充值 2,000 澳元。
In addition to the living allowance stipend, the successful applicant will receive student allocation funding of up to $6,000 towards ancillary project costs such as conference travel.
除了生活津贴外，成功的申请人还将获得高达 6,000 澳元的学生分配资金，用于支付会议旅行等辅助项目费用。
International students will receive a full tuition fee sponsorship.
国际学生将获得全额学费赞助。
Eligibility/application criteria
资格/申请标准
You must have: 您必须具备：
- recently completed a BSc Hons degree or equivalent in a relevant field (bioinformatics, microbiology, genomics or biochemistry)
最近完成了相关领域（生物信息学、微生物学、基因组学或生物化学）的荣誉学士学位或同等学历 - received first-class honours (H1) or equivalent
获得一等荣誉 （H1） 或同等学历 - excellent communication skills, motivation and the ability to work as part of a team
出色的沟通技巧、积极性和团队合作能力 - a general interest in microbiology and ideally you will also have experience with bioinformatics
对微生物学有普遍的兴趣，理想情况下，你也会有生物信息学方面的经验 - meet the academic eligibility requirement as set out in the QUT How to Apply website: QUT - How to apply
满足 QUT 如何申请网站中规定的学术资格要求：QUT - 如何申请
How to apply 如何申请
Submit your expression of interest to Associate Professor Simon McIlroy at simon.mcilroy@qut.edu.au
将您的意向书提交给 simon.mcilroy@qut.edu.au 的 Simon McIlroy 副教授
Your application must include:
您的申请必须包括：
- a cover letter indicating which project(s) you are most interested in
一封说明您最感兴趣的项目的求职信 - an up-do-date CV 最新的简历
- full academic transcript 完整的成绩单
- a summary (up to 2 pages) of your research career to date
您迄今为止的研究生涯摘要（最多 2 页） - details of three referees (email/address/contact number).
三名推荐人的详细信息（电子邮件/地址/联系电话）。
Application closing date 申请截止日期
This opportunity will remain open until filled.
此机会将一直开放，直到填满为止。
For more information 了解更多信息
Please contact Associate Professor Simon McIlroy (simon.mcilroy@qut.edu.au) and/or Professor Phil Pope (phil.pope@qut.edu.au) for further information.
请联系 Simon McIlroy 副教授 （simon.mcilroy@qut.edu.au） 和/或 Phil Pope 教授 （phil.pope@qut.edu.au） 了解更多信息。
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